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Drug Information: a Guide for Pharmacists, 7th Edition by Call Number: Ebook linked & print edition in Library: QV 737.1 D793 2022ISBN: 9781260460308Publication Date: 2022
Drug Information Question Intake Form
- Drug Information Question Intake Form - University of FloridaFrom University of Florida College of Pharmacy, this Drug Information Question Intake/Tracking Form includes all fields that could be used in a formal drug information
service setting.
It will lay out all the information you need to keep track of to complete a drug information request.
Start Here
1. Find the right information resource to use for your drug question category.
2. Use Drug Databases to:
- Get information on how to safely use individual drugs from drug monographs
- FDA drug labels provide free access to this information
- Check for interactions
- Check IV compatitbility
- Identify pills
Exercise: Compare major drug databases. How they arrange information and what information they contain will matter to you.
3. Use medical reference tools or textbooks, like DiPiro's, to:
- Review a disease or condition
- Review treatment options
4. Use Clinical Practice Guidelines to:
- Identify current therapeutic standards for specific conditions
5. Use clinical trials and other research articles to:
- Identify new treatments in development and investigational drugs
- Find research relevant to a complex or specific clinical situation or patient
- Perform background research or literature review on a topic
6. Check for mobile apps.
7. Prepare for journal club.
- 2025 APPE BOOTCAMPLibrary presentation slides
Drug Information Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information.
- UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
- Micromedex This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
- NatMed This link opens in a new windowEvidence-based information on alternative and complementary medicine
- USP-NF United States Pharmacopeia-National Formulary
An e-book of public pharmacopeial standards for medicines, dosage forms, drug substances, excipients, medical devices, and dietary supplements. Create a free account for access.
Log in with an existing account
Register for a USP account
Medical Reference Tools
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
- Merck Manual Professional Version This link opens in a new windowFree evidence summaries on disease states, treatments, labs, procedures and more including clinical pharmacology, critical care medicine, dental disorders, and procedure videos.
Mobile access information Merck Manual Mobile Apps.
Free Drug Information Websites
- ASHP Drug ShortagesDrug product shortages and management information from American Society of Health-System Pharmacists (ASHP).
- Consumer Product Information Database
Consumer and household products, including ingredients, potential health effects, safe handling and disposal.
- DailyMedDrug listings and full label information (package inserts) from the FDA.
- Dietary Supplement Label DatabaseDietary supplement labels with product information, ingredients, and manufacturing.
- Drugs.com Pill Identifier
Read the terms and accept them to use this site.
- Drugs@FDAFDA Approved Drug Products. Patient information, labels, approval letters, reviews, and other information.
- FDA Drug ShortagesCurrent and resolved drug shortages and discontinuations as reported to the U.S. Food and Drug Administration.
- LactMed
Reference source for drugs to which breastfeeding mothers may be exposed.
- LiverToxInformation on the diagnosis, cause, and management of liver injury attributable to medications, herbals, and dietary supplements.
- The Medical LetterCritical appraisals of new prescription drugs and comparative reviews of drugs for common diseases.
- National Drug Code Directory (NDCs)The NDC maintained by the FDA serves as universal product identifier for human drugs.
- Orange Book FDAApproved Drug Products with Therapeutic Equivalence Evaluations. The products approved under section 505 of the Federal Food, Drug, and Cosmetic Act.
Drug Information Databases by Question Category
General, Product-Related
Drug Databases
(Provided by Roseman University Library)
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Package Insert
- DailyMedDrug listings and full label information (package inserts) from the FDA.
Adverse Effects
Medical Quick Reference
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Administration, Drug
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Antimicrobial Therapy
The Sanford guide to antimicrobial therapy 2021, 51st ed by Call Number: Print edition in Library: QV 250 S224 2021ISBN: 9781944272180Publication Date: 2021
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Bioequivalence
(free option)
- Orange Book FDAApproved Drug Products with Therapeutic Equivalence Evaluations. The products approved under section 505 of the Federal Food, Drug, and Cosmetic Act.
Calculators (pharmaceutical; medical)
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Medical Quick Reference
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
Free Options
Clinical Trials, Investigational Drugs
- Cochrane Library This link opens in a new window
Systematic reviews, clinical trial registry and clinical answers tools.
- PubMed This link opens in a new window
Biomedicine and life sciences journal articles from MEDLINE and PubMed Central.
Set up a personal NCBI account to set alerts and collections of results. - Clinical Trials This link opens in a new windowClinical trial registry for the US and global research.
Comparative Tables
- Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps.
Contraindications
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Compounding
Trissel's Stability of Compounded Formulations by Call Number: QV 735 T837 2018ISBN: 9781582122960Publication Date: 2018-01-31
- USP-NF United States Pharmacopeia-National FormularyAn e-book of public pharmacopeial standards for medicines, dosage forms, drug substances, excipients, medical devices, and dietary supplements. Create a free account for access.
Log in with an existing account
Register for a USP account
Martindale: The Complete Drug Reference by Call Number: Ebook linked & print edition in Library: QV 738.FA1 M384 2020ISBN: 9780857113672Publication Date: 2020
Cost
- Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Free Option
- GoodRx
GoodRx is a free mobile app and website that helps Americans find the lowest prescription prices in their neighborhood.
Dietary/Herbal Supplements
- NatMed This link opens in a new window
Evidence-based summaries on alternative and complementary medicine including foods, herbs, supplements, brands and manufacturers, interaction checker and pregnancy and lactation information.
Free options
- Dietary Supplement Label DatabaseDietary supplement labels with product information, ingredients, and manufacturing.
- FDA Dietary SupplementsFrom the Food section of the FDA website, find updates, consumer information, or report a problem with dietary supplements.
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Diseases, Diagnosis
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
(DiPiro's) Pharmacotherapy: a Pathophysiologic Approach, 12th Edition by Call Number: Ebook linked & print edition in Library: WB 330 P535 2023ISBN: 9781264264544Publication Date: 2023
Harrison's Principles of Internal Medicine, 21st Ed by Call Number: Ebook linked & print edition in Library: WB 115 H322 2022ISBN: 9781264268504Publication Date: 2022
- Clinical Key This link opens in a new window
Medical reference books, journal articles, drug information, disease and skill overviews, videos, and practice guidelines.
Free Option
- Merck Manual Professional Version This link opens in a new windowFree evidence summaries on disease states, treatments, labs, procedures and more including clinical pharmacology, critical care medicine, dental disorders, and procedure videos.
Mobile access information Merck Manual Mobile Apps.
Dosage
Drug Databases
See the Clinical Practice Guidelines sections:
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Free Option
- DailyMedDrug listings and full label information (package inserts) from the FDA.
Drug Identification
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Free Option
- Drugs.com Pill IdentifierRead the terms and accept them to use this site.
Drug Interactions
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Foreign/International Drugs
Free Options
- Drugs.com InternationalThe Drugs.com international drug name database contains information about medications found in 185 countries around the world. The database contains more than 40,000 medication names marketed outside the USA and is presented in multiple languages.
- Canadian Drug Product Database
Search the Drug Product Database (DPD) to find drugs authorized for sale by Health Canada. The DPD is updated nightly and includes:availability of the drug in Canada, product monographs for human drugs, and labels for animal drugs. - European Medicines Agency
Search the medicine finder to find information on medicines authorised for human or veterinary use. You can find these by including the medicine's name or its active substance. - WHO International Pharmacopoeia
The International Pharmacopoeia is comprised of a collection of recommended procedures for analysis and specifications for the determination of “pharmaceutical substances” (active pharmaceutical ingredients), excipients and “dosage forms” (general texts and individual finished pharmaceutical products) that is intended to serve as source material for reference or adaptation by any World Health Organization (WHO) Member State wishing to establish pharmaceutical requirements.
Immunization Schedules
Free Options
- CDC Vaccine Schedules
Make sure your patients stay up to date on recommended vaccines using these schedules. - CDC Vaccine Schedules App for Health Care ProvidersCDC app to identify correct vaccine, dosage, and timing with just 2 or 3 clicks.
IV Compatibility
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
ASHP Injectable Drug Information 2023 by Call Number: QV 737.1 A819 2023ISBN: 9781585286836Publication Date: 2022-11-30
Nonprescription/Over-the-Counter products
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Handbook of Nonprescription Drugs by Call Number: QV 57 H236 2020ISBN: 9781582123172Publication Date: 2020
Patient Counseling/Education
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Free Option
- MedlinePlus
Free. Consumer health database, including drugs, supplements, and herbal information as well as a medical dictionary, medical encyclopedia, health tutorials and more. Available in Spanish.
Pharmacokinetics
Drug Databases
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Pharmacotherapeutics
(see also Therapeutics)
- (DiPiro's) Pharmacotherapy: a Pathophysiologic Approach, 12th Edition by Call Number: Ebook linked & print edition in Library: WB 330 P535 2023ISBN: 9781264264544Publication Date: 2023
Goodman and Gilman's the Pharmacological Basis of Therapeutics, 14th Edition by Call Number: Ebook linked & print edition in Library: QV 4 G653 2022ISBN: 9781264258079Publication Date: 2022
Katzung's Basic and Clinical Pharmacology, 16th Edition by Call Number: Ebook linked & print edition in Library: QV 4 B311 2020ISBN: 9781260463309Publication Date: 2023
Pharmacy/Medical News
- Pharmaceutical News Index This link opens in a new windowPharmacological news, research, and regulatory information. News and journal articles from pharmaceutical, health care, biotechnology, and medical device industries.
Free Options
- Prescriber Insights
Prescriber Insights (formerly Prescriber's Letter) is the fastest, most trustworthy way to find out how drug therapy changes should fit into your practice, all while earning monthly CME credit. It's 100% free from financial support of the pharma industry. - Pharmacy Times
Publication providing clinical information and continuing education for pharmacists.
Pregnancy/Lactation
Briggs Drugs in Pregnancy and Lactation by Call Number: Ebook linked & print edition in Library: WQ 39 D794 2021ISBN: 9781975162375Publication Date: 2021
Briggs is also available via UpToDate Lexidrugs
- UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Free Option
- LactMedReference source for drugs to which breastfeeding mothers may be exposed.
Therapeutics
(See also Pharmacotherapeutics)
- UpToDate This link opens in a new windowComprehensive evidence summaries for disease states, diagnostics, labs, medical calculators, guidelines, drug information and more.
Login to UpToDate using your Roseman network credentials (choose Institutional or OpenAthens sign in options from the mobile app or website). You will be prompted to register for an account the first time.
Condition-specific
Search for Clinical Practice Guidelines
- Locate Clinical Practice Guidelines - Pharmacy Program GuideResources and databases to find, use, and apply clinical information
Toxicology/Poisoning
- LiverTox
LiverTox® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and dietary supplements. - Consumer Product Information DatabaseConsumer and household products, including ingredients, potential health effects, safe handling and disposal.
Drug Databases
Go to Toxicology sections
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information. - Micromedex This link opens in a new window
Drug monographs, drug prices (Red Book), interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information Pharmacy Mobile Apps. - UpToDate Lexidrug This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Student discounts on Lexicomp Handheld.
Patient Safety
- FDA Investigational New Drug Application (IND)Instructions for submitting an emergency IND.
- The Infection Prevention and Control Portal - The Joint ComissionStandards for processes, practices, policies, and procedures relating to infection control. The Joint Commission accredits and certifies nearly 21,000 health care organizations and programs in the United States.
- Institute for Safe Medication PracticesSafety alerts
Confused drug names
High alert medications
Plus guidelines, continuing education, and more.
- MedWatchFDA Safety Information and Adverse Event Reporting Program
- Morbidity and Mortality Weekly Report (MMWR) - CDCThe CDC's weekly reports on public health information and recommendations.
- National Patient Safety Goals (NPSGs) - The Joint CommissionPatient safety goals for accredited institutions.The Joint Commission accredits and certifies nearly 21,000 health care organizations and programs in the United States.
Check their patent safety fact sheets for a "Do Not Use" list of abbreviations.
Do Not Crush Lists
- Clinical Pharmacology This link opens in a new window
Do Not Crush List is under the "Lists" heading on the front page
Patient Education Resources
Read beneath each link to find a pathway to handouts and information patient education.
- 5 Minute Consult This link opens in a new windowSelect "For The Patient" > "Patient Handouts." Available in English or Spanish.
- Care Notes System This link opens in a new windowPatient education information about all aspects of patient care, medications, and health, in English or Spanish.
- Clinical Key This link opens in a new windowSelect "Patient Education." Available in multiple languages.
- Clinical Pharmacology This link opens in a new windowDrug monographs, interaction checkers, IV compatibility, clinical calculators, drug ID and more.
Mobile access information.
- MedlinePlusFree. Consumer health database, including drugs, supplements, and herbal information as well as a medical dictionary, medical encyclopedia, health tutorials and more. Available in Spanish.
- Merck Manual - Consumer VersionA great reference for disease states, drugs, and more in plain language.
- U.S. Food and Drug Administation (FDA) - For ConsumersConsumer information from the FDA with alerts, recalls, etc. available in both English and Spanish.
Health Literacy in Medicines Use and Pharmacy by Call Number: eBook linkedISBN: 9780128244074Publication Date: 2024-11-28
Jump to Your Question Category
General, Product-Related; Adverse Effects, Administration, drug; Antimicrobial Therapy; Bioequivalence; Calculators; Clinical Trials, or Investigational Drugs; Comparative Tables; Contraindications; Compounding; Cost; Dietary or Herbal Supplements; Diseases or Diagnosis; Dosage; Drug Identification; Drug Interactions; Foreign/International Drugs; Immunization Schedules; IV Compatibility; Nonprescription or Over-the-Counter Products; Patient Counseling or Education; Pharmacokinetics; Pharmacotherapeutics; Pharmacy and Medical News; Pregnancy and Lactation; Therapeutics; Toxicology or Poisoning
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